cell transformation meaning in English
细胞转化
Examples
- The process of neoplasia begins with cell transformation
肿瘤形成源于细胞转化。 - Cell transformation test
细胞转化试验 - Blast cell transformation
母细胞转化 - There is lobular disarray with focal hepatocyte necrosis , giant cell transformation , lymphocytic infiltration , kupffer cell hyperplasia , and cholestasis ( not seen here )
图中可见具有病灶肝细胞坏死、巨细胞转化、淋巴细胞浸润、枯否细胞增生和胆汁淤积（此图未显示）的肝小叶紊乱。 - Phopholipase c - 1 ( plc - 1 ) is widely known to play an important role in regulating cell proliferation and differentiation , development of the organisms , cell transformation and oxidative stress . till now , the mechanism how phopholipase c - 1 acts can not be thoroughly illustrated , nor has the interaction between plc - 1 pathway and other signal pathways been systematically reported . this research chose 2 - de + ms as the basic method from all kinds of proteomics strategies and compared the total protein expression map of mef genetically deficient in plc - 1 ( plc - 1 - / - ) to that of wild type mef ( plc - l + / + ) aimed to find some protein spots differentially expressed , thus we can discuss the impact of knockout of plc - 1 on signal transduction initiated by growth factors such as egf comprehensively . in this way , we can study the biological function of plc - 1 and mechanism of plc - 1 pathway indirectly , which will contribute a lot to further analysis
鉴于plc - 1发挥上述作用的机制尚未完全阐明， plc - 1通路与其他信号通路间的交联和代偿尚无系统报道，又因为以往的研究方法不够全面，本研究以野生型小鼠胚胎成纤维细胞( plc - 1 ~ ( + / + ) )和缺失磷脂酶c - 1的小鼠胚胎成纤维细胞( plc - 1 ~ ( - / - ) )为研究模型，在众多蛋白组学策略中选择了双向电泳+质谱( 2 - de + ms )作为研究手段，通过对比表皮生长因子( egf )刺激24小时后上述两种细胞的总蛋白质表达差异，全面地探讨敲除plc - 1对生长因子诱导的信号传递的影响，从而间接研究plc - 1生物学作用、信号传递机制及其代偿情况，为后续的深入研究打下基础。